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Clinical Data Phase 2 clinical studies of cagrilintide monotherapy in adults with obesity reported dose-dependent weight reductions of 6.0% to 10.8% over 26 weeks with a favourable tolerability profile

These are different problems with different solutions

Collectively, these studies support the versatile antibacterial potential of CQDs through various mechanisms, however, most evidence remains derived from in vitro systems, with limited in vivo validation and safety profiling, highlighting the need for further evaluation prior to clinical translation

The nomination did not include the safety, identity, and clinical-rationale data the agency needs to evaluate

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